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Dimethylmalate dehydrogenase
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Dimethylmalate dehydrogenase : ウィキペディア英語版
Dimethylmalate dehydrogenase

In enzymology, a dimethylmalate dehydrogenase () is an enzyme that catalyzes the chemical reaction
:(R)-3,3-dimethylmalate + NAD+ \rightleftharpoons 3-methyl-2-oxobutanoate + CO2 + NADH
Thus, the two substrates of this enzyme are (R)-3,3-dimethylmalate and NAD+, whereas its 3 products are 3-methyl-2-oxobutanoate, CO2, and NADH.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-3,3-dimethylmalate:NAD+ oxidoreductase (decarboxylating). This enzyme is also called beta,beta-dimethylmalate dehydrogenase. This enzyme participates in pantothenate and coa biosynthesis. It has 5 cofactors: ammonia, manganese, cobalt, potassium, and NH4+.
==References==

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